Assessment of Alcohol Exposure: Testing for Ethylglucuronide (Etg), Ethylsulfate (Ets)

Alcohol use disorder is a leading cause of preventable death with serious consequences in many domains. There is an increasing need to fine tune detection and diagnostic methods to enable health care workers prevent, diagnose and manage this disorder. The diagnosis of an alcohol problem could be quite a challenge as the disorder can present as other psychiatric syndromes. The diagnostic armamentarium includes good history and clinical examination, screening tools and biomarkers. Biomarkers are divided into direct and indirect physiologic biomarkers and two of these, namely EtG and EtS, are proving to be a great asset in guiding clinicians to determine alcohol consumption, retrospectively, over many days.